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Tri Fade 

Being intoxicated on three substances simultaneously.

Generally Alcohol, Marijuana, and some other substance. The third ingredient is really personal preference but some popular choices include:

Mushrooms,
Morphine,
Cocaine,
Vicodin,
Oxy,
Nicotine,
Caffeine.

A good trifecta is the nicotine, weed, alcohol which gets you in a good party mood and balancing the three types of buzz is very important.
Dude 1: I had an amazing Tri Fade going last night. I smoked two blunts, was dipping for for like an hour and then pounded 5 beers and 6 shots.

Dude 2: Sounds nice. Tobacco focuses the senses, Alcohol makes you want to party, and weed just makes it all feel so pleasant.

Dude 1: Hell yeah, I'm trying the Quad Fade next friday!
Tri Fade by CHS 2010 January 28, 2010
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Tri-Faded 

Being on 3 different drugs at one time
I was so tri-faded last night
Tri-Faded by Alex Clark October 11, 2018
Related Words

trifaded 

When you are on three substances at the same time.

For example: Drunk, high on weed and tripping on acid.

Overall, a good time.
Yo dawg, yesterday I got so trifaded I thought the sky turned mellow-yellow
trifaded by Johny Faded January 28, 2014