Powerpuff 

A preppy, girly person.

A Powerpuff walked by wearing a mini purse.

Powerpuff by BubleeZ November 18, 2005

Powerpuff 

puff, puff, PUFF. pass.

dat guushyyt: wait, is it puff, or puff puff?
juicy shyyt: nigga it's powerpuff!
dat guushyyt: hell yea

Powerpuff by the shyyts. March 22, 2009

Powerpuff 

Awesome, a most richeous thing, cool, mondo, da bomb, just so damn powerpuff!

Dude, that is just so powerpuff.

Powerpuff by Greg July 30, 2003

Powerpuff 

A term for a crybaby republican who has trouble accepting the election results and moving on. They can be seen asking non sensical questions regarding laptops, emails and texts, and generally calling democrats “snowflakes”.

Look at that white supremacist crying about the election and telling anyone who will listen to ask about hunter biden’s laptop, what a Powerpuff little girl.

Powerpuff by The Bird Man June Ya April 10, 2021

Powerpuff Girls

Sugar. Spice. And everything nice.

These were the ingredients chosen to create the perfect little girl.

But Professor Utonium accidentally added an EXTRA INGREDIENT to the concoction.... CHEMICAL X.

Thus, the POWERPUFF GIRLS WERE BORN!

Using thier ultra super powers,
BLOSSOM, BUBBLES, and BUTTERCUP have dedicated their lives to FIGHTING CRIME and the FORCES. OF. EVIL!!!

Basically.

"Holy cow, it's MoJo JoJo! Somebody call the Powerpuff Girls!"

Powerpuff Girls by ~JMan January 10, 2009

powerpuff presentation 

A powerpoint presentation containing lots of flashy animations, cool pictures, and all sorts of other snazzy gimmics, but almost entirely lacking in any real substance.

Didn't the VP's presentation just blow you away? I loved the falling apples turning into dollar bills.

But what was the point?

Dunno; it was definitely a powerpuff presentation.

powerpuff presentation by jigsawz67 March 26, 2011

Powerpuff Girls Z 

A 2006 Japanese anime spin-off of the original American Show "The Powerpuff Girls". This anime was drawn by the same artists who worked on the Sailor Moon series. The anime is also produced by Cartoon Network, Toei Animation, and Aniplex even though the creator of the original show (Craig McCracken) did not take any part in this.The anime aired in Japan on July 1, 2006 and has yet to come to the U.S. or any other countries for that matter, but Cartoon Network said that the anime will be aired worldwide. The Ocean Group announced that they will dub the anime into English but they are not sure if it's going to make it to american television, or if the voice actors from the original show will voice act for the anime.

Powerpuff Girls Z is a pretty good, for a spin-off of an original show.

Powerpuff Girls Z by Alex Hills May 2, 2007