A Powerpuff walked by wearing a mini purse.
by BubleeZ November 9, 2005
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puff, puff, PUFF. pass.
dat guushyyt: wait, is it puff, or puff puff?
juicy shyyt: nigga it's powerpuff!
dat guushyyt: hell yea
by the shyyts. March 22, 2009
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Awesome, a most richeous thing, cool, mondo, da bomb, just so damn powerpuff!
by Greg July 30, 2003
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1) A series of sexual acts involving shit, Diet Coke and Mentos, cum, saliva, vomit, or a combination of each. If done in the right order, these sex acts (mainly Blossom) can severely damage a girl's vagina. For obvious reasons, they must be done in this order: Blossom, Bubbles, and Buttercup.

2) Blossom, Bubbles, and Buttercup. Created by Professor Utonium after he accidentally added Chemical X to his mixture of "sugar, spice, and everything nice" while trying to make the "perfect little girl." See their names for more info regarding the sex acts mentioned above.

3) An animated children's television franchise centered around the girls mentioned above.
1) Guy 1: I did the Powerpuff Girls with my sister last night
Guy 2: how was it?
Guy 1: FUCKIN' INCREDIBLE!

2) And so, once again, the day is saved thanks to the Powerpuff Girls!

3) Remember when The Powerpuff Girls was good? Pepperidge Farm remembers!
by Yopmail User July 9, 2022
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Sugar. Spice. And everything nice.

These were the ingredients chosen to create the perfect little girl.

But Professor Utonium accidentally added an EXTRA INGREDIENT to the concoction.... CHEMICAL X.

Thus, the POWERPUFF GIRLS WERE BORN!

Using thier ultra super powers,
BLOSSOM, BUBBLES, and BUTTERCUP have dedicated their lives to FIGHTING CRIME and the FORCES. OF. EVIL!!!

Basically.
"Holy cow, it's MoJo JoJo! Somebody call the Powerpuff Girls!"
by ~JMan January 11, 2009
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A powerpoint presentation containing lots of flashy animations, cool pictures, and all sorts of other snazzy gimmics, but almost entirely lacking in any real substance.
Didn't the VP's presentation just blow you away? I loved the falling apples turning into dollar bills.

But what was the point?

Dunno; it was definitely a powerpuff presentation.
by jigsawz67 March 10, 2011
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Best show ever. 'Nuf said.
Them there Powerpuff Girls kick ass!
by Vanessa December 11, 2004
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