A Squire is person who does not do psychedelic drugs (LSD, psilocybin containing mushrooms, DMT, or Salvia) They are said to be "uncool" and not aware the the world the way psychedelic drugs uses are. A squire has no third eye.
In the movie "Jay and Silent Bob Strike Back" a mother leaves her child outside the Quickstop in a stroller as she runs in. A passerby questions her parenting for leaving said child outside said Quickstop. The mother calls the passerby a "Fucking Squire!"