A person using a tesseract in three-dimensional space would be equivalent to a person using three dimensions to move through a two-dimensional universe. The laws of physics would still apply, but only on the two-dimensional scale.
The Nietzscheans are a race of genetically engineered humans who quite religiously follow the works of Friedrich Nietzsche, Social Darwinism and Dawkinite genetic competitiveness. They claim to be physically perfect and are distinguished by bone blades protruding outwards from the wrist area.
The Nietzschean betrayal of the Commonwealth ended in mutual devistation, and the known universe was left in chaos.