1. The remark made when an individual reaches a moment of bliss through extreme chilling, usually in the midst of or following smoking the chronic.
2. Expressing great happiness after learning of good news.
Brewskis: Yo I brought down some pizza
Pop: Nice Dude Nice
Pop: Oh i just found another pound of white rhino.
Brewskis: Nice Dude Nice
When sitting two rows behind the sixers bench at a sixers cavs game.