When smoking marijuana, that one infamous hit that nudges you from sober to high. Usually occurs five to ten minutes into the smoking session, depending upon the quality of the weed. If the weed's super dank, one might Anthony Bourdain on the first hit, though this is rare (and would consequently enable one to appropriately declare, "Noooo reservations!").
Named for the popular chef/host/tour guide who is known for his liberal attitude towards mind-altering substances and who was, incidentally, on television when this phenomenon was being named.
Seymour had been smoking with his friend Mortimer for a few minutes when he suddenly felt the stirrings of a good high. "Ah... I just Anthony Bourdained," he announced.
"There she blows," answered Mortimer.
Jane took her third hit from the bong. As she slowly released the smoke from her lungs and felt her extremities start to tingle, she realized that the hit was her Anthony Bourdain.