3 definitions by Big Poppi

A 50/50 mix of Powder Heroin and Powder Cocaine. Creates the feeling of being in a relaxing warm bathtub mixed with the desire to complete an insurmountable task. This volatile mix is usually mixed into a drink because snorting it is too risky.
Guy 1: "I heard that guy over there is selling "screwball"."
Guy 2: "That stuff will mess you up for days."
by Big Poppi July 29, 2014
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The condition in which someone becomes so hooked to the drug Alprazolam that they begin to lose a large quantity of weight.
"Damn, she needs to chill on taking so many bars. She has lost so much weight I think she might have Xanorexia."
by Big Poppi September 22, 2016
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Dude, Grabua just got dipset.
by Big Poppi August 22, 2008
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