wtfizz Share definition Flag "wtfizz" is used online and is read as "What the fizz". It's another way of saying "What the hell" or "What the fuck". John: Hey do you know we have a test on friday? George: wtfizz! we do? I didn't know that! wtfizz by Cylex December 13, 2007 0 0 Get merch Get the wtfizz mug. Buy Now — $32.95 See more merch