When something said or done is so wrong, that one cannot help but feel disdain for it on numerous metaphysical tiers.

That is to say, it breaches what is considered 'right' in more ways than one.
Person 1: 'I don't know how to tell my girlfriend that I cheated on her with her grandma...'
Person 2: 'Dude, that's just wrong on so many levels'.
by grandad_dwarf March 7, 2016
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It can mean both literally, something that is wrong from different points of view, and figuratively, something that is extremely wrong.
+This is what I believe about crime rate in black people's community.
-Well, that was wrong on so many levels.
by amshahriar May 15, 2016
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