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When a girl thinks too highly of herself and insults others she is up herself. Literally means she is masturbating herself. Mainly used in Ireland/England.

Meg: Anabel still isn't talking to us...
Emma: I know, that bitch is so up herself...
by Mr. Zed December 11, 2006
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Oct 3 Word of the Day
I couldn’t care less (but one must keep up appearances, right?)
Frenemy has a family tragedy. "Thoughts and prayers."
by November 05, 2018
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