To be easily noticed. To have something obvious going on.
Jane: Do you think i should put on my multi colored hat & gown?

John: No i don't. You're just gonna stick out like a sore thumb.
by mehcee March 29, 2014
Dude, you should quit driving by my house in that blue car and parking it at the bakie shop!
Your front plate sticks out like a sore thumb. It's all red and say's omni... * * *saves on it. It your trying to be incogneeto your doing a horrible job of it. e.g. Stop calling me a liar too. You dont see me driving by your place like a nause with a cause. Boom shacka, ya loud mouth chicken shit!