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From spastic, the disability.

Means a person that acts insane or mentally retarded.

A certain person with strange common sense that just cannot be explained.
Yeh Hannah’s just being a spazio again.
Spazio by Chromosome69 March 7, 2020
Related Words
Her sweetness kindness and everything about her makes me whole entire day she means the whole entire world to me thanks for coming in my life.
I love you spazoe
spazoe by - your bsf <3 May 26, 2021

spazmoid 

A variation on spaz that carries all the same possible meanings.. following in the red dwarf 'gimboid' tradition. Particularly appropriate to nerdy people.
Dude get some friends and stop being such a spazmoid
spazmoid by pdizzler91 June 2, 2011
Heil Hitler! Nein, don't heil Hitler, er ist ein SPAZI!
Spazi by Verkaiser July 28, 2011
Tablets for spazz attacks.
The doctor prescribed Christine spazzo tablets
spazzo by Toerag January 23, 2008
Australian slang for a retarded person - spastic, spazo, spazzo. Usually not used to refer to a genuinely disabled person, but a moron. Also further abbreviated to spack.
"Jeez Gazza's a spazo. He cracked onto a total babe at the pub last night and was too shitfaced to root her".
spazo by Lucyfanclub May 14, 2008