Pound of fifties Share definition Flag A hyperbolically very large amount of money equal to one pound of fifty dollar bills. Joe: "Hey I'm going to the store, you need anything?"Matt: "Yeah, get me a pound of fifties, Bruh" Pound of fifties by electromatt August 11, 2009 0 0 Get merch Get the Pound of fifties mug. Buy Now — $32.95 See more merch