pickyfied Share definition Flag Adjective. Southern African-American. Constantly being picky and petty about things, specifically "hood" disputes. Making a major i issue about something small I can't believe that ho done called the police over some bullshit, that bitch be real pickyfied. pickyfied by Onetime August 31, 2012 0 0 Get merch Get the pickyfied mug. Buy Now — $32.95 See more merch