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Meaning weak rubbish and used predominantly by emos and the sci-fi computer gaming community in response to statement or question you disagree with to imply the same. Entered the lexcon via my space/faceparty and similar social e-networking sites.
example 1 - Conversation on an internet forum relating to anime characters from the Final Fantasy 7 plysation game.

- Sepiroth's cute
- pfsssh look at Seph he looks like a demented clown without make-up

- But you're blond, all the guys like you
- pfsssh being blonde doesn't mean anything!!! i was actually thinking of going back again..=\
pfsssh by Samantha Welch December 27, 2008
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Pssshh is a word that often is seen on the internet, meaning "Yea, whatever," or "Oh please."
Kate said "I have cooler shoes than you do."

Julia replied "Pssshh!"
pssshh by Julia Donovan December 16, 2004
Related Words
pfsssh pissshit psssh Pfsss Pissshh psssh-er Psssh ET pssshh Pssshhh pssshhhh
An expression of dissatisfaction or disagreement often used in conjunction with a one eye eyebrow raise.

Also an expression of share frustration caused by ones collegues, usually on a Harley.

Originally found in the depths of Upper Hutt, New Zealand.

ET is pronounced "eahhtt" not E T.
Psssh ET!
Psssh ET by Ant O Saurus May 26, 2010
A: "yo aint gotz no skeyulz"
B: "psshhh thatz not wut yo momz sayd"
Pssshhh by chris October 23, 2002

pssshhhh 

we got a history test tommorrow

pssshhhh
pssshhhh by Ethan January 27, 2005
essentially the word 'psssh' means...

-the simple sound that i am making with my mouth is much better than everything you just said.

-can also mean, 'i don't care'
or
-'you are full of shit'
or
-used to express amusement

it is a word that reduces the worth of any previos speech, elevating itself to a higher level of conversation, language and vocabulary.

it is frankly, the ultimate word.
where is the work i asked you to do?
-psssh!

did you see that goal? it was amazing!
-psssh!

isn't that the guy with loads of STDs?
-psssh!

i drink loads of alcohol, i bet i drink more than you do!
-psssh!

i bet im better than you at.......
-psssh!

personaly i believe that the christian faith......
-psssh!

you get the point
psssh by toke urbz September 22, 2006

psssh-er 

Someone who sells hard drugs (cocaine, crack, LSD, heroin, XTC) in Amsterdam. They got the name because if people walk past them they say "psssh" which basicly means: "hey do you wanna score some drugs?"
Tourist walks past this guy
Drug dealer: Psssh
Tourist: huh?
Drug dealer: Hey man wanna score some dope?
Tourist: sure!
psssh-er by Dick_H July 18, 2005