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1. To experience discomfort or illness as a result of overindulgence or overexposure to something or someone. Usually pertains to overindulgence of sweet or fattening foods, but could also apply to a person.
1. Michelle was completely ostigated after eating a whole pack of gummy bears in the movie theatre.

2. John's presence is totally ostigating me; his aura is just so overwhelming.
by SCOTTinScotland November 08, 2005
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