The nope train is a train you take when you see something that scares or extremely disturbs you. When things like this happen you simply say: "that you are taking that nope train".
by Randybutternubs October 11, 2014
A MEME you use when posting your extreme disgust or disagreement with some one's post on Facebook or Twitter
When Hillary Clinton asked Bernie Sanders supporters to vote for her during the 2016 Presidential election more than 95% of his hard core supporters were taking the Nope Train to Fuck This shitsville
by Mister Spock 95 March 1, 2017