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Otaku (Heavy fans of Japanese cartoons) slang for a cat girl. Literally meaning "Cat-ear" in Japanese. Usually a girl in cosplay (costume) wearing homemade cat ears and tail of their favorate character from an anime series (Japanese cartoon).

Note: Can also be someone of a cat-humanoid race, as in a mithra from Final Fantasy XI.
A more literal meaning of Nekomimi in Japanese is Nekomusume (cat daughter or cat girl).
nekomimi by Draken Stark August 14, 2006
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Nekomimi is when a cute cat girl is crying. #nekomimi
Did you just nekomimi at me?
Nekomimi by xXxNekoxXx December 8, 2019