1)someone or something that literaly or metaphoricaly kicks ass

2) someone or something that causes great damage to anything it comes in contact with.

3) a large angery person who scares the shit out of you

4) a tremendously effective implement of destruction, usually a weapon

5) something someone declares themselves after kicking ass
stay away from that big guy over there, he's a murder machine

yo, that 1911 i just bought is a murder machine

(while standing over your half dead opponent) I Am A MURDER MACHINE!
by fuckov March 5, 2008