A disease in which the infected person cannot make anything that doesn't suck. Those infected have been known to have give horrible direction, have extremely crude and vulgar ways of going about things, be offensive toward human beings, and give people who have been exposed to their creations diseases such as cancer and Lou Gerhig's Disease.
-"Man, watching Transformers 2 gave me cancer, the director must have suffered from Michael Bay Disease"
by Fat Val Kilmer March 7, 2014