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This is a typical Italian expression created by a viral Youtuber. It is an expression of disappoiment
When we want to insult we can use it.

"Sei un lezzo, mahonna"
"You are a lezzo, Madonna"
Lezzo by Blillo December 13, 2016
Related Words
A Lesbian Hedgehog. A hedgehog that is reported to eat other hedgehogs minges.
Lilly the lesbian lezhog was munching mandies spiny minge. (because mandy is a lezhog too)
Homosexual females seen as noticeably overweight and often associated with short haircuts, snout noses, and male-like physical characteristics while seen as generally unattractive to the opposite sex; see 'Butch' for further reading.
I don't think anything could have prepared me for the sight of two lezhogs going at it earlier in the park.
Lezhog by dave creedance April 11, 2009
lesbian in turkish slang,sonds english
mr and mrs brown and two lezzos are going to the beach
lezzo by lolitadrame August 7, 2003
Lezog is a lesbian hedgehog
She's a proper lezog
Lezog by Guntherrrrrr September 7, 2014
A term meaning "lesbian". It can be used in a derogatory manner, but isn't a slur. Many lesbians use it, often in a comedic manner.
See that girl over there- you think she's a lezzo? Oh- tegan and sara tee. I'm gonna go talk to her.
Lezzo by that homosexual June 11, 2018