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Combination of "truffle butter" and "kerfuffle," meaning any life situation in which shit is really messed up and in total disarray.
How's your job going, bro?

Dude, it's total kerfuffle butter right now at my job: Paychecks are late, the VP is thinking of quitting, someone just filed a lawsuit against the company, and customers are bailing by the boatloads.
by Ae5Ea8 April 07, 2015
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