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Used as a term of endearment towards a friend, but that is still on the mean side. Used to call a friends a hoe or bitch because they did something but is meant to say it in a more friendly or playful way and not a I'm gonna kick your ass kinda way. It has a wider range of uses.
Sammi just got the number of a guy you were checking out at the party, she's such a hoeknuckle. Or. You hoeknuckle !!!
by Drew Biltmore February 12, 2017
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