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1.)Doing cocktail of various prescribed drugs and/or narcotics entering the body all at once.

2.)ingesting or injecting a nearly lethal amount drugs in the body continuously without rest for extended period of time.
1.)Robbie is highloading on crack,weed,and everclear since he came home from prison.

2.) Ever since Joe fell off the trampoline he has been highloading himself for days now with those pain pills.

by lil quwezy January 19, 2013
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