Somebody that has that straight savage thug mentality because they are stuck in the hood.

They are most likely to put in work and setup shop and slang.
I got so many fools that are tripping off me, but I ain't slippin' I got that ghetto sickness.
by KRosenrot April 4, 2016
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a term used to define super cool or awesome. its a combination of the word sick(cool) and ghetto is just put in front of the word to make it sound rad
jasmine: hey jc did you see the white honda mini-van with the automatic sliding doors

jasmine: yea boii those doors are ghetto sick.
by dina-boi March 8, 2009
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Term used to describe when a female from the ghetto gets pregnant, but thinks she is sick so she constantly drinks orange juice to alleviate her "sickness".
"Yo, why Mary keep drinking OJ? She sick?"
"Nah, that jawn ghetto sick."
by jawnyjawnjawn December 7, 2009
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