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Fregna is a synonym of the word Fica or Figa, and it literally means vagina.

We usually use it to refer to a very beautiful woman, it exists also the word Fregno, which is used for handsome men.
It's largely used in central part of Italy.
Ammazza che fregna! = Wow, what a beautiful woman!
Fregna by alelololol September 28, 2017
Related Words
Synonym for fica, fregna is the most vulgar Italian term to indicate a vagina, and indeed rather similar to the English word cunt.

It is often used together with the adjective "dry", as in "dry cunt", in Italian: "fregna secca".

The reference is mostly metaphorical in this expression, so usually not to a non-lubricated vagina, but rather more to a woman who is boring, rigid, uninspiring, no fun, skinny and wrinkly.
"Ma che fregna secca!" = "What a dry cunt!"
fregna by Gleufje March 21, 2017
it means how old is your brain
i’m feeling pretty frogna today

FROGNALFLAT 

FROGNALFLAT:- The centre of FROGNAL life and trade, the heart and home of LONDON'S creativity, trade and triumph.
I'll have to get back up to my FROGNALFLAT, leave me alone for the rest of the day - I'll get back onto you when I can, should be early tonight.
FROGNALFLAT by FABARM January 17, 2019
Both free and legal
Last Sunday, I enjoyed the legit fregal orange juice at my hotel.

Homework should not be fregal.
Fregal by rubbersoulXD April 2, 2010
Spanish term for harrassing, bugging, and annoying someone.
"Voy a fregar a la maestra!" meaning I am going to annoy the teacher.

"Como friegas!" meaning "what a pain in the ass!"
"Esas son fregaderas!" meaning "that's a bunch of bullshit!"
Fregar by Kuntif Divsalar April 30, 2010