1. The complete loss or absence of hope

2.An utter loss of hope; a feeling of uselessness, often brought about through contact with a greeter at Wal- Mart.
'Greeter: Hey, welcome to Wal-Mart

You: ugh (Despair)...
by thesarcasmguy January 3, 2016
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I was taking a shit and I ran out of paper so I looked under the sink for despair
by thegreanmonster February 5, 2017
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This is opposite of 'Hope'. You are basically very sad and angy.
Nagito (from danganronpa) dislikes this very much
kokichi: I'm in desp-

nagito: son I told you not to say swear words in public

kokichi: but father, I am in despair. My ice cream melted :(
by Boop Ee the best June 2, 2021
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Despair is a religion where we worship the queen junko enoshima.We will say these exact words while worshipping her “despair is best” we will watch the tsgumi and junko edit daily.Finally after all that we bully nagito :)
Person-So your in what now?!
Me- despairism!
Person-is that even real?! And what’s it abt?

Me- yes I created it! And I’ll explain later!
by Pixelcandy November 9, 2020
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The feeling you get when there is no food in the fridge.
I feel despair when I don't what I want.
by Olive Oil 98 November 13, 2017
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Despair; to feel hopeless and no feeling of joy whatsoever, to despair.
This word has also been claimed by the Danganronpa fandom, nobody else can use it.
Hajime: Mikan Tsumiki, you're the culprit!
Monokuma: Punishment tiiiime!
Mikan: This feeling of despair~!
by irumatsu_53 June 6, 2021
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