When a guy has a skin discoloration on his penis resulting in spots.
1: Did you see Ryan's penis?
2: No, why?
1: He has spots.
2: Oh, so dalmatian syndrome.
by Phillip Joebob Fisher VI November 4, 2010
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Placeholder name for the next inevitable, currently undiscovered animal-related disease.
Richard: First mad cow disease, then Asian bird flu, now swine flu; I can't *wait* for dalmatian syndrome!
Vincent: Shit, there's a new one!?
Richard: No, it's the codename for the next big one.
by PracticalVal September 4, 2009
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