An insult used to describe a stupid or ignorant person, taken from the scientific term "anencephalous", meaning "without brain".
"You cephy, how did you not know that?"
by eagle553 April 3, 2019
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to fuck up without a clue as to how or why
He pulled a cephie and now she has a chipped tooth
by optimus prime 180 October 26, 2007
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