a condition men exhibit in a prolonged situation lacking attractive women. In this environment the least ugly girl becomes attractive over time due to a lack of options.
Man1: Girl X is looking good today..

Man2: Are you joking? You need to drop out of engineering school, your getting brookes syndrome from being couped up with those nerds all day.
by PartyStone October 21, 2010
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When an out-of-touch celebrity makes an out-of-touch announcement for their new, out-of-touch account on a different platform.
Matthew McConaughey has come down with a severe case of Garth Brooks syndrome, because his Instagram announcement video was unbearable.
by Mydadcalledmeaboomer November 7, 2019
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