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1. To express contempt, surprise, or general dissatisfaction.
2. John Kane as being the substitution for any and all vulgar expletives/slang.
Guy #1: I just cut off my finger!
Guy #2: What the John Kane!

Mr. Deane: Where is all your homework? What the John Kane is going on here?
by JohnKaneAdmirer February 07, 2010
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