Wayne-iac Share definition Flag A person who has an uncontrollable obsession with the greatest rapper alive, Lil Wayne, and wants to get 'Weezy F. Baby' tattered on their butt. All that girl listens to is Lil Wayne. She's a wayne-iac! Wayne-iac by weezyfbaby123 May 3, 2010 Get the Wayne-iac mug.