To be so obsessed with trannies that you are incapable of shutting up about them, and blame them for all of modern society's problems. Victims of Tranny Derangement Syndrome will bring up their hatred of trannies in literally any online discussion, no matter what is being discussed, and stir up pointless drama among people that don't give a shit.

The conservative analogue of Trump Derangement Syndrome.
"What does sex change surgery have to do with a thread about computers? No one wants to hear about this gross shit. Fuck off with the Tranny Derangement Syndrome, no one cares."

"STFU DILATE AND KYS TRANNY"
by dontkillalljewspls April 1, 2020
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