Top definition
exactly what it sounds like. a disk drive that, instead of reading disks, dispenses tissues. usually made by gutting an entire computer, putting a tissue box inside, and pulling the tissues out through the disc drive.
"man, i need to refill my Tissue disc drive. I was sneezing a ton last night and I ran out!" "i couldnt find any tissues to insert into the computer though."

by thekittykat October 13, 2011
Happy St. Patties Day!