knowing something special, exciting or dangerous will happen soon
with will's spider sense he was able to avoid the gang bang that happend down the alley he decided not to walk down.
by bob dylan October 9, 2003
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A sixth sense that tingles when there's something else wrong with someone or something.
Spidey-I think there's something else wrong with the guy, my spider sense is tingling.
Other guy-Something else wrong with the guy besides the alien he just gave birth to out of his stomach? What do you know that I don't know spider man?
by Solid Mantis August 24, 2018
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What is said sarcasticly when a slow-witted somebody discovers that things are not as they appear long after everyone else has assumed it. Derived spiderman
This car is still making a rattling sound, are you sure you fixed it?

My spider sense is tingling.
by Kung-Fu Jesus April 30, 2004
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