Roast Beef Syndrome Share definition Flag A brown discoloration on the vaginal lips, often seen on porn stars. When I went down on Tina, she had some wicked Roast Beef Syndrome that reminded me of an Arby's Big Montana Roast Beef Syndrome by Scott Riel February 14, 2004 0 0 Get merch Get the Roast Beef Syndrome mug. Buy Now — $32.95 See more merch