A phrase you say when you're playing video games late at night (possibly on substances) and you see/do something so crazy that you have no other words to say.
Jeremiah: GOD DAMN THAT BITCH JUST PULLED THE ONE-TWO JIMBO POOP ON HIS HEADASS

Tyler: Jerry what the fuck are you talking about
by JimmyLikesBones October 1, 2021
Get the One-Two Jimbo Poop mug.