Top definition
To perform anal sex while using Sanitizing gel as a lubrication shortly after defecating.
Guy: "O baby, you just took a crap? Wanna do a Missouri Drain-O real quickly to clean it out?"
Girl: "I'd love to"
by mexichode6969 January 17, 2010
Get the mug
Get a Missouri Drain-O mug for your grandma Helena.
Oct 3 Word of the Day
I couldn’t care less (but one must keep up appearances, right?)
Frenemy has a family tragedy. "Thoughts and prayers."
by November 05, 2018
Get the mug
Get a Thoughts and prayers mug for your cousin Vivek.

Activity