The characteristic retroverted, backward leaning posture that some obese people develop as a survival mechanism to counteract their extreme weight-forward balance. Most likely to develop in individuals who frequent fried food joints in the Deep South. Can also be used to describe the walking-stumble gait of a person who has had one too many drinks, artificially replicating the individual described formerly.
Example 1:

Friend A, inside a hole in the wall restaurant: "What are you laughing at?"
Friend B: "Don't turn around just yet. There's a habitual customer behind you who has the Mississippi Lean going on."

Example 2: "Did you see that lady leaving the bar? She's got that Mississippi Lean—her husband had to sit her down outside to prevent her from falling backwards."
by CallsignSkywalker December 19, 2022
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