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Used to refer to extreme levels of loneliness.

Michael Collins the astronaut. He was one of the three persons aboard on Apollo 11 crew. The other two Neil Armstrong and Buzz Aldrin got to walk on the moon, whilst Michael Collins was sitting in the command module alone. In fact, for 45 minutes, when he was on the other side of the moon which didn't face the Earth, he not only lost contact with NASA on Earth, but with both Armstrong and Aldrin, making him one of the loneliest person in human history.
Matt: I feel lonely this Valentine's Day.

Dave: You may be lonely, but not Michael Collins lonely.
by InternetHuman September 17, 2016
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