Top definition
When a straight man sees another man that is so cute, he would go gay for that one particular man.
Johnny Depp is so freakin' cute, I would totally turn gay for him. I think I'll diagnose him with what I'll call, Johnny Depp Syndrom.

Man, Tim has Johnny Depp Syndrome....
by Sigjap April 06, 2011
Get the mug
Get a Johnny Depp Syndrome mug for your friend Trump.