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Similar to a "Moose Knuckle" and a "Camel Toe", A Goose Knuckle means a floppy or loose vagina that is clearly visible through a woman's pants, bathing suit, tights, etc.
Guy 1: "Dude did you see that chick?!"
Guy 2: "Ya man, major Goose Knuckle!"
Guy 1: "Thats pretty grody, i think i even heard it moving around down there."
by JSPINS January 19, 2011
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