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When one's ability to give a fuck has been removed (medically or otherwise). Occurs spontaneously when someone gives too many fucks and has none left to give. Sometimes necessary as a medical intervention when someone gives too many fucks to a point where it is detrimental to their well-being.
1. Dude, let it go. You really need a giveafuckendectomy.

2. "Wow, what's up with Sarah?" "She had a giveafuckendectomy, because she don't give a fuck."
by Etceteraz May 24, 2018
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