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Ghettero is a slur between Ghetto and Hetero. Ghetto has come to mean almost anything now days. But all in all it usally means strait up or extreme. Hetero means strait like heterosexual is oriented to the opposite sex. So pretty much Ghetero is strait up extreme, boss , awesome, the bomb.
"whoa! no school today? that's ghettero bruhh"
by bruddah-C January 06, 2010
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