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When you have to urinate really bad, generally when you are drunk or inebriated by other means.

Originating from the term Genocide- in this case to mean "really bad"
and leak, to urinate.
"Drive fasta' man I gotta genoleak"

"You can tell by the way that I move my pants,
I got the Genoleak, no time to speak.
ah, ah, ah, ah Genoleak, Genoleak."
-To the tune of stayin' alive
by FINKLESTINK September 24, 2008
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