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When you eat at Friendly's and you get sick from it (diarrhea). Named so because Friendly's is a "happy name" and to be "Blue" is to be sad.
Person #1: I ate at Friendly's last night.

Person #2: Oh no! Did you get the Friendly's Blues?

Person #1: Ya...I was on the toilet all night, blasting shit out of my ass.

Person #2: I'm not going to eat there again.

Person #1: Good idea...
by Darknessoni69 February 13, 2009
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