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Acronym for "Easier said than done". In other words, the task at hand is easy to discuss but would be far more difficult to actually accomplish.
<Pinky> Let's take over the world, Brain!
<Brain> ESTD, Pinky...
ESTD by Dr Fruitcake July 27, 2004
Related Words
Pronounced ee-stid, is an electronic STD contracted from viewing too much internet porn.

i.e. a computer virus
Your computer is slow as shit! How many fucking E-STDs have you got?
E-STD by D-Lines December 9, 2008