Top definition
When a member of the opposite sex looks good from afar but looks far from good.
Guy 1: "Dude, check out that hot chick across the street!"
Guy 2: "Hell yeah, here she comes!"
Guy 1: "Ewww. She's not hot at all. She's got Distance Disease!"
by G.Funk January 29, 2010
Get the mug
Get a Distance Disease mug for your daughter-in-law Yasemin.