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A nick name applied to Dr Dan Poulter, Minister for Health in the UK coalition Government that took office in 2010. The epithet emerged after Dr Poulter's apparently spurious claims to have regularly worked over 100hours per week when training as a junior doctor. This would have been illegal following the European Working Time Directive (EWT) and exposed the hospitals Dr Poulter worked for to considerable fines.
The following is a hypothetical Twitter conversation.

Dr Poulter - Whut up yo? Things have changed for these young'uns since back in the dayz. I be puttin in post-EWT WORK fo my scrilla

Dr Deveson (Arch Nemesis of D100) - Sit yo punk ass down fool, and quit 'yo bitchin. You don *know* work. You a D100!

Dr Dan - You crossed a line mane. Im oudda Twitter. This shit is whack.
D100 by @Jeremy_Twunt September 10, 2012
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a 100 sided die, specifically used in RPGs The d100 was invented by Lou Zocchi, and is patented as the "Zocchihedron". Although the d100 is not a true polyhedra, it is a sphere with 100 surfaces. There can be somewhat of a learning curve for reading the Zocchihedron correctly, but... It's much geekier to roll a d100 for a percentage rolls than 2 d10's.
Palladium games often require a lot of percentile rolls, that's why I bought my first d100.

Haha suckaz, critical hit, doing 2d100 damage, take that!
d100 by protocoldroid July 20, 2004
Related Words

D100 Dice 

A dice so large and full of so many numbers that it is truly a ball: Once you roll it, it will NEVER come back
Bob: I shall buy the D100 Dice for D&D

Jimmy: No dude you will lose it it is round

Bob: Naw bro I will get it

*Two seconds later*

Bob: Crap I lost it

*Dice rolling into the sewer grate*
An Irish phrase meaning shit, derived from ass
(Not to be confused with the literal description of one's buttocks)
"Did you hear the song Aylek$ dropped?"
"Hardly. Her music is absolute cheeks."

"My boyfriend say LaFlame is cheeks."
"Tell your boyfriend I said it's his mixtape that's cheeks."
Cheeks by thecartisan April 26, 2020

sans sheriff 

Lawless use of fonts or typography, with no regard to aesthetics or legibility
I'm putting this CV straight in the bin. Written totally sans sheriff.
sans sheriff by Jamarley July 3, 2019

Breadhead 

Someone who is addicted to obtaining money and building wealth. A money addict and fanatic. Breadheads often work more than one full-time job, and some even participate in illicit activities to "obtain the bread".
A breadhead is like a crackhead, but for money instead of crack.
Breadhead by 🅱️ U S 3 4 8 March 30, 2022

Stink lines

As seen in illustrations or cartoons: Wavy, vertical lines rising above a person, place or thing. Denotes a foul odor.
"You didn't put enough stink lines on your picture of the teacher."
Stink lines by Athene Airheart March 14, 2004